IGF (Long Chain Human Insulin Growth Factor 1-R3) 1mg – Keifei Pharma

Description

Insulin-like growth factor 1 is a hormone that functions as the major mediator of growth hormone (GH)-stimulated somatic growth, as well as a mediator of GH-independent anabolic responses in many cells and tissues. Insulin-like growth factor-1 is a small peptide (molecular weight 7647) that circulates in serum bound to high affinity binding proteins. IGF-1 is an unusual peptide in this regard since it is more than 99 percent protein-bound.

IGF-1 is synthesized by multiple mesenchymal cell types. As a result, there are two major mechanisms of Insulin-like growth factor-1 regulation:

• GF-1 that is synthesized in the liver and secreted into the blood is under the control of GH.
• Autocrine/paracrine IGF-1 is synthesized in peripheral tissues, such as bone. Its synthesis is controlled by GH and by factors that are secreted locally by the surrounding cell types. Some of the secreted autocrine/paracrine Insulin-like growth factor-1 enters the systemic circulation. Therefore, understanding the regulation of autocrine/paracrine synthesis of IGF-1 is necessary to interpret changes in serum Insulin-like growth factor-1 concentrations.

IGF-1 exerts its effects via activation of the Insulin-like growth factor-1 receptor. This receptor is widely distributed, which enables blood-transported Insulin-like growth factor-1 to coordinate balanced growth among multiple tissues and organs. In contrast, autocrine/paracrine IGF-1 can stimulate local, unbalanced growth independently of systemic GH. Examples of this type of growth regulation are wound healing and growth of the contralateral kidney after unilateral nephrectomy.

Dosage Instructions

Injected via Subcutaneous injection after a workout at 20 mcg – 100 mcg / day with a typical cycle length of 4-6 weeks.

Side Effects

Taking growth hormone can impact how the body responds to insulin which controls blood glucose levels. Untreated growth hormone deficiency can lead to high cholesterol and osteoporosis. Although growth hormone injections are relatively safe and effective, there are a few side effects. Fortunately, serious side effects are rare.

Swelling, numbness, and joint and muscle aches and pains are the most common side effects. You may experience these side effects if you’re getting more growth hormone than you need.

If you have these symptoms, talk to the physician immediately to adjust the amount of growth hormone you are taking.

Some possible side effects with IGF-1/LR3 could be:

• Joint pain
• Muscle pain
• Headaches
• Nausea
• Hypoglycemia
• May be associated with an increased risk of developing a number of common cancers, including lung, breast, colorectal, and prostate